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introduction : "Wang Y, Zhou X, Wang Y, Gong X, Tang Y, Zhang Y, Liu H, Huang Y, Lin Z, Liu J*,Pan L* (2024) \"STK4 inhibits the E3 activity of HOIP by phosphorylating its allosteric ubiquitin-binding site\" PNAS (under revision)",
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introduction : "Zhang J, Li M, Wang Y, Liu H, Gong X, Zhang Y,Pan L* (2024) \"Molecular basis of the interaction of Optineurin with Rab8a\" J. Mol. Biol. (under revision)",
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introduction : "Zhang Y, Sun Y, Shi J, Xu P, Wang Y, Liu J, Gong X, Wang Y, Tang Y, Liu H, Zhou X, Lin Z, Baba O, Morita T, Yu B*,Pan L* (2024) \"Decoding the molecular mechanism of selective autophagy of glycogen mediated by autophagy receptor STBD1\" PNAS (In press)",
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introduction : "Zhang M, Wang Y, Gong X, Wang Y, Zhang Y, Tang Y, Zhou X, Liu H, Huang Y, Zhang J ,Pan L* (2024) \"Mechanistic insights into the interactions of TAX1BP1 with RB1CC1 and mammalian ATG8 family proteins\" PNAS 121(11):e2315550121",
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introduction : "Qin Y, Li D, Qi C, Xiang H, Meng H, Liu J, Zhou S, Gong X, Li Y, Xu G, Zu R, Xie H, Xu Y, Xu G, Zhang Z, Chen S, Pan L, Li Y, Tan L* (2024) \"Structure-based development of potent and selective type-II kinase inhibitors of RIPK1\" Acta Pharmaceutica Sinica B.14, 319-334",
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introduction : "Cui S, Xia T, Zhao J, Ren X, Wu T, Kameni M, Guo X, He L, Guo J, Duperray-Susini A, Levillayer F, Collard JM, Zhong J ,Pan L, Tangy F, Vidalain PO, Zhou D, Jiu Y, Faure M, Wei Y* (2023) \"NDP52 mediates an antiviral response to hepatitis B virus infection through Rab9-dependent lysosomal degradation pathway\" Nat. Commun. 14(1):8440",
aticleUrl : "source/publication/2023/2023-011.pdf"
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introduction : "Zhang Y, Xu X, Wang Y, Wang Y, Zhou X ,Pan L* (2023) \"Mechanistic insights into the homo-dimerization of HOIL-1L and SHARPIN\" BBRC.689:149239",
aticleUrl : "source/publication/2023/2023-012.pdf"
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introduction : "Xu X, Wang Y, Zhang Y, Wang Y, Yin Y, Peng C, Gong X, Li M, Zhang Y, Zhang M, Tang Y, Zhou X, Liu H, ,Pan L* (2023) \"Mechanistic insights into the enzymatic activity of E3 ligase HOIL-1L and its regulation by the linear ubiquitin chain-binding\" Sci. Adv. 9(41):eadi4599",
aticleUrl : "source/publication/2023/2023-005.pdf"
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introduction : "Qiu X, Li Y, Wang Y, Gong X, Wang Y ,Pan L* (2023) \"Mechanistic insights into the interactions of Arl8b with the RUN domains of PLEKHM1 and SKIP\" J. Mol. Biol. 435(22):168293",
aticleUrl : "source/publication/2023/2023-006.pdf"
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introduction : " Xue Y, Li M, Hu L, Liu J,Pan L*, Liu W* (2023) \"Mechanistic Investigations into the Catalytic Mode of a Dehydratase Complex Involved in the Biosynthesis of Lantibiotic Cacaoidin\" CJC 41, 3579-3586",
aticleUrl : "source/publication/2023/2023-007.pdf"
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introduction : " Zhao Y, Liu X, Xiao Z, Zhou J, Song X, Wang X, Hu L, Wang Y, Sun P, Wang W, He X, Lin S, Deng Z, ,Pan L, Jiang M* (2023) \"O-methyltransferase-like enzyme catalyzed diazo installation in polyketide biosynthesis\" Nat. Commun. 14(1):5372",
aticleUrl : "source/publication/2023/2023-008.pdf"
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introduction : "Zhang T, Xu D, Liu J, Wang M, Duan LJ, Liu M, Meng H, Zhuang Y, Wang H, Wang Y, Lv M, Zhang Z, Hu J, Shi L, Guo R, Xie X, Liu H, Erickson E, Wang Y, Yu W, Dang F, Guan D, Jiang C, Dai X, Inuzuka H, Yan P, Wang J, Babuta M, Lian G, Tu Z, Miao J, Szabo G, Fong GH, Karnoub AE, Lee YR,,Pan L, Kaelin WG Jr, Yuan J*, and Wei W* (2023) \"Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation\" Nat.Cell. Biol. 25, 950-962.",
aticleUrl : "https://www.nature.com/articles/s41556-023-01170-4"
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introduction : "Ding W, Zhou M, Li H, Li M, Qiu Y, Yin Y, Pan L, Yang W, Du Y, Zhang X, Tang Z, Pan L, Liu W*,(2023) \"Biocatalytic Fluoroalkylation Using Fluorinated S-Adenosyl-l-methionine Cofactors\" Organic Letters..25, 5650-5655.",
aticleUrl : "source/publication/2023/2023-010.pdf"
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introduction : "Zhang T, Xu D, Trefts E, Lv M, Liu J, Liu M, Chu C, Wang M, Wang H, Meng H, Liu H, Zhuang Y, Xie X,Dang F, Jiang C, Dai X, Lee Y, Inuzuka H, Erickson E, Hillis A, Dibble C, Miao J, Asara J, Szabo G, Sicinski P, Pan L*, Shaw R*, Yuan J*,and Wei W*,(2023) \"Metabolic Orchestration of Necroptosis and Inflammation through AMPK-Mediated Phosphorylation of RIPK1\"Science.380, 1372-1380.",
aticleUrl : "source/publication/2023/2023-003.pdf"
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introduction : "Gong X, Pan L*, (2023) \"ATG16L1 is equipped with two distinct WIPI2-binding sites to drive autophagy\" Autophagy.14;1-3.",
aticleUrl : "https://www.tandfonline.com/doi/full/10.1080/15548627.2023.2213038?scroll=top&needAccess=true&role=tab"
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introduction : "Gong X, Wang Y, Tang Y, Liu J, Wang Y, Xu X, Zhang M, Li M, Zhang Y, Pan L*,(2023) \"ATG16L1 adopts a dual-binding-site mode to interact with WIPI2b in autophagy\" Sci. Adv..9(9):eadf0824..",
aticleUrl : "source/publication/2023/2023-001.pdf"
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introduction : "Feng K, Zhang Y, Zhang M, Yang Y, Liu J, Pan L*, and Zeng Y*,(2023) \"Biochemical and structural basis for a flavin-monooxygenase catalyzing oxepinone formation and the complete biosynthesis of vibralactone\" Nat. Commun.14(1):3436.",
aticleUrl : "source/publication/2023/2023-004.pdf"
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introduction : "Wang H, Zou Y, Li M, Tang Z, Wang J, Tian Z, Strassner N, Yang Q, Zheng Q, Guo Y, Liu W*, Pan L*, and Houk K* ,(2023) \"A cyclase that catalyses competing 2+2 and 4+2 cycloadditions\" Nat Chem.. 15, 177-184.",
aticleUrl :"source/publication/2023/2023-002.pdf"
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introduction : "Liu Z, Chen K, Dai J, Xu P, Sun W, Liu W, Zhao Z, Bennett SP, Li P, Ma T, Lin Y, Kawakami A, Yu J, Wang F, Wang C, Li M, Chase P, Hodder P, Spicer TP, Scampavia L, Cao C,Pan L, Dong J, Chen Y*, Yu B*, Guo M*, Fang P*,Fisher DE*, Wang J*, (2023) \"A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy\" Cell Res..2023, 33, 55-70.",
aticleUrl : "https://www.nature.com/articles/s41422-022-00744-5"
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introduction : "Liu G, Du Y, Fu T, Han Y, Pan L, Kang J* , (2022) \"Profiling protein interactions by purification with capillary monolithic affinity column in combination with label-free quantitative proteomics\" J Chromatogr A..2022, 1676:463273.",
aticleUrl : "source/publication/2022/2022-002.pdf"
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introduction : "Liu J, Wang Y, Wang D, Wang Y, Xu X, Zhang Y, Li Y, Zhang M, Gong X, Tang Y, Li M, Pan L *, (2022) \"Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri\" PNAS .2022, 119(12):e2116776119.",
aticleUrl : "source/publication/2022/2022-001.pdf"
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introduction : "Fu T, Zhang M, Zhou Z, Wu P, Peng C, Wang Y, Gong X, Li Y, Wang Y, Xu X, Li M, Shen L,Pan L *, (2021) \"Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52\" Sci. Adv. .2021, 7(33):eabi6582.",
aticleUrl : "source/publication/Before2022/2021-001.pdf"
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introduction : "Meng H, Wu G, Zhao X, Wang A, Li D, Tong Y, Jin T, Cao Y, Shan B, Hu S, Li Y,,Pan L,Wu P, Tian X, Peng C, Yuan J, Li G, Tan L, Wang Z *, (2021) \"Discovery of a cooperative mode of inhibiting RIPK1 kinase\" Cell. Discov..2021. 7(1):41.",
aticleUrl : "source/publication/Before2022/2021-002.pdf"
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introduction : "Shan H, Liu J, Shen J, Dai J, Xu G, Lu K, Han C, Wang Y, Xu X, Tong Y, Xiang H, Ai Z, Zhuang G, Hu J, Zhang Z*, Li Y*,Pan L *, Tan L*,(2021) \"Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2\" Cell. Chem. Biol. 2021, 28, 855-865.",
aticleUrl : "source/publication/Before2022/2021-003.pdf"
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introduction : "Zhou Z, Liu J, Fu T, Wu P, Peng C, Gong X, Wang Y, Zhang M, Li Y, Wang Y, Xu X, Li M,Pan L *, (2021) \"Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation\" Nat. Commun..2021,12(1):1570.",
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introduction : "Pischedda F, Cirnaru M, Ponzoni L, Sandre M, Biosa A, Carrion M, Marin O, Morari M, Pan L, Greggio E, Bandopadhyay R, Sala M, Piccoli G* ,(2021) \"LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation\" Brain..2021, 144, 1509-1525.",
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introduction : "Zhang H, Lin L, Liu J, Pan L, Lin Z, Zhang M, Zhu J*, Zhang R* ,(2021) \"Phase separation of MAGI2-mediated complex underlies slit diaphragm assembly in glomerular filtration barrier\" Journal of the American Society of Nephrology..2021, 32(8):1946-1960.",
aticleUrl : "https://jasn.asnjournals.org/content/32/8/1946.long"
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introduction : "Daniel J. Klionsky*, et al and Pan L, and et al ,(2021) \"Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th edition)\" Autophagy..2021, 17, 1-404.",
aticleUrl : "source/publication/Before2022/2021-007.pdf",
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introduction : " Hua K, Liu X, Zhao Y, Gao Y, Pan L, Zhang H, Deng Z, Jiang M* ,(2020) \"Offloading Role of a Discrete Thioesterase in Type II Polyketide Biosynthesis\" mBio.2020, 11, 01334-20.",
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introduction : "Li Y, Cheng X, Li M, Wang Y, Fu T, Zhou Z, Wang Y, Gong X, Xu X, Liu J,Pan L *, (2020) \"Decoding three distinct states of the Syntaxin17 SNARE motif in mediating the autophagosome- lysosome fusion\" PNAS.2020,117, 21391-21402. (Recommended by Faculty Opinions)",
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introduction : "Xu X, Liu J, Wang Y, Wang Y, Gong X, Pan L *, (2020) \"Mechanistic insights into the interactions of Ras subfamily GTPases with the SPR domain of autism-associated SHANK3\" CJC.2020, 38, 1635-1641.",
aticleUrl : "source/publication/Before2022/2020-003.pdf"
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introduction : "Liu G, Fu T, Han Y, Hu S, Zhang X, Zheng M, Hao P, Pan L *, Kang J*, (2019) \"Probing Protein–Protein Interactions with Label-Free Mass Spectrometry Quantification in Combination with Affinity Purification by Spin-Tip Affinity Column\" Analytical Chemistry.2020, 92, 3913-3922.",
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introduction : "Hu S, Guo Y, Wang Y, Li Y, Fu T, Zhou Z, Wang Y, Liu J, Pan L *, (2019) \"The structure of the Myosin VI and Tom1 complex reveals a unique cargo recognition mode of Myosin VI for tethering\" Nat. Commun..10(1):3459.",
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introduction : " Liu J, Li Y, Pan L *,（2019）\"Structural Basis of Autophagy Regulatory Proteins\" Advances in Experimental Medicine and Biology.1206:287-326.(invited Book chapter review).",
aticleUrl : "source/publication/Before2022/2019-002.pdf"
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introduction : "Fu T, Liu J, Wang Y, Xie X, Hu S, Pan L *, (2018) \"Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1\" PNAS..115,E11651- E11660.",
aticleUrl : "source/publication/Before2022/2018-008.pdf"
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introduction : "Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zuo C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito M, Meng H, Y Li, Pan H, Aron L,Adiconis X, Levin J, Yankner B, Yuan J.* ,(2018) \"TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging\" Cell..174, 1477-1491.",
aticleUrl : "https://www.sciencedirect.com/science/article/pii/S0092867418309693"
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introduction : "Liu J, Pan L. *, (2018) \"Structural bases of the assembly, recognition and disassembly of linear ubiquitin chain\" BBA - Mol.Cell.Res..1865, 1410-1422.(invited review)",
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introduction : "Hu S, Wang Y, Gong Y, Liu J, Li Y, Pan L. *, (2018) \"Mechanistic Insights into Recognitions of Ubiquitin and Myosin VI by Autophagy Receptor TAX1BP1\" J. Mol. Biol..430, 3283-3296.",
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introduction : "Zheng Q, Gong Y, Guo Y, Zhao Z, Wu Z, Zhou Z, Chen D, Pan L. *,Liu W.* , (2018) \"Structural Insights into a Flavin-dependent [4+2] Cyclase that Catalyzes trans-Decalin Formation in Pyrroindomycin Biosynthesis\" Cell. Chem. Biol.. 25, 718-727.",
aticleUrl : "source/publication/Before2022/2018-002.pdf"
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introduction : "Perez Carrion, M., Pischedda, F., Biosa, A., Russo, I., Straniero, L., Civiero, L., Guida, M., Gloeckner, C., Ticozzi, N., Tiloca, C., Mariani, C., Pezzoli, G., Duga, S., Pichler, I., Pan L., Landers, J., Greggio, E., Hess, M., Goldwurm, S.*, Giovanni-Piccoli, G.* , (2018) \"The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1 \" Front. Mol. Neurosci.. 11:64.",
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introduction : "Li F, Xu D, Wang Y, Zhou Z, Liu J, Hu S, Gong Y, Yuan J, Pan L. *, (2018) \"Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation \" Autophagy. 14, 66-79.",
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introduction : "Zhang, Z., Gong, Y., Zhou, Q., Hu, Y., Ma, H., Chen, Y., Igarashi, Y., Pan, L. *,Tang, GL.* , (2017) \"Hydroxyl regioisomerization of anthracycline catalyzed by a four-enzyme cascade \" PNAS. 114,1554-1559.",
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introduction : "Xu, D., Liu, J., Fu, T., Shan, B., Qian, L., Pan, L. *, Yuan, J.* , (2017) \"USP25 Regulates Wnt Signaling by Controlling the Stability of Tankyrases \" Genes. Dev.. 31, 1024-1035.",
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introduction : "Wei,R., Xu, L., Liu, J., Li, Y., Zhang, P., Shan, B., Lu, X., Qian, L., Wu, Z., Dong, K., Zhu, H., Pan, L. , Yuan, J.* , Pan,H.*,(2017) \"SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination \" Genes. Dev.. 31, 1162-1176.",
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introduction : "Liu, J., Wang, Y., Gong, Y., Fu, T., Hu, S., Zhou, Z., Pan, L. *, (2017) \"Structural Insights into SHARPIN-mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly \" Cell Rep..21(1):27-36.",
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introduction : "Zheng, Q., Guo, Y., Yang, L., Zhao, Z., Wu, Z., Zhang, H., Liu, J., Cheng, X., Wu, J., Yang, H., Jiang, H.,, Pan, L. *,Liu, W.* , (2016) \"Enzyme-Dependent [4 + 2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4 \" Cell Chemical Biology.. 23, 352-360.",
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introduction : "Cheng, X., Wang, Y., Gong, Y., Li, F, Guo, Y., Hu, S., Liu, J., Pan, L. *,(2016) \"Structural Basis of FYCO1 and MAP1LC3A Interaction Reveals a Novel Binding Mode for Atg8 Family Proteins\" Autophagy. . 12,1330-1339.",
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introduction : "Li, F., Xie, X., Wang, Y., Liu, J., Cheng, X., Guo, Y., Gong, Y., Hu, S., Pan, L. *,(2016) \"Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins\" Nat. Commun. . 7:12708.",
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introduction : "Gong, Y., Pan, L., * (2015) \"Recent advances in bioorthogonal reactions for site-specific protein labeling and engineering \" Tetrahedron Letters.. 56, 2123–2132.",
aticleUrl : "source/publication/Before2022/2015-001.pdf"
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introduction : "Xia, H., Najafov, A., Geng, J., Galan-Acosta, L., Han, X., Guo, Y., Shan, B., Zhang, Y., Norberg, E., Zhang T., Pan, L., Liu J., Coloff, J., Ofengeim, D., Zhu, H, Wu, K., Cai, Y., Yates, JR., Zhu, Z., Yuan, J.*, Vakifahmetoglu-Norberg, H , (2015) \"Degradation of HK2 by Chaperone-Mediated Autophagy promotes Metabolic Catastrophe and Cell Death \" J. Cell Biol. . 210, 705-716",
aticleUrl : "source/publication/Before2022/2015-002.pdf"
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introduction : "Xie, X., Li, F., Wang, Y., Wang, YL., Lin, Z., Cheng, X., Liu, J., Chen, C., Pan, L.*, (2015) \"Molecular Basis of Ubiquitin Recognition by Autophagy Receptor CALCOCO2 \" Autophagy. . 10, 1775-1789.",
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introduction : "Xu, D., Shan, B., Lee, B., Zhu, K., Zhang, T., Sun, H., Liu, M., Shi, L., Liang, W., Qian, L., Xiao, J., Wang, L.,, Pan, L. ,Finley, D., Yuan, J.*, (2015) \"Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system \" eLife..4:e10510.",
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introduction : "Yan B, Han P, Pan L, Lu W, Xiong J, Zhang M, Zhang W, Li L, Wen Z. * (2014) \"IL-1β and reactive oxygen species differentially regulate neutrophil directional migration and Basal random motility in a zebrafish injury-induced inflammation model\" J Immunol. 192, 5998-6008.",
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introduction : "Piccoli G, Onofri F, Cirnaru MD, Kaiser CJ, Jagtap P, Kastenmüller A, Pischedda F, Marte A, von Zweydorf F, Vogt A, Giesert F, Pan L, Antonucci F, Kiel C, Zhang M, Weinkauf S, Sattler M, Sala C, Matteoli M, Ueffing M, Gloeckner CJ *(2014) \"Leucine-Rich Repeat Kinase 2 Binds to Neuronal Vesicles through Protein Interactions Mediated by Its C-Terminal WD40 Domain\" Mol. Cell. Bio. 34, 2147-2161.",
aticleUrl : "source/publication/Before2012/2014-002.pdf"
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introduction : "Vakifahmetoglu-Norberg, H., Kim, M., Xia, HG., Iwanicki, MP., Ofengeim, D., Coloff, JL., Pan, L., Ince, TA., Kroemer, G., Brugge, JS., Yuan, J. *(2013) \"Chaperone-mediated autophagy degrades mutant p53\" Genes. Dev. 27, 1718-1730.",
aticleUrl : "source/publication/Before2022/2013-Chaperone-mediated autophagy degrades mutant p53.pdf"
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introduction : "Yu, C., Luo, J., Wu, J., Pan, L., Feng, W. and Zhang, M.* (2012) \"Membrane-induced lever arm expansion allows myosin VI to walk with large and variable step sizes\" J. Biol. Chem. 287, 35021-35035.",
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introduction : "Wu, L.#, Pan, L.#, Zhang, C., and Zhang, M.* (2012) \"Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia\" J. Biol. Chem. 287, 33460-33471. (#:co-first authors)",
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introduction : "Li, X., He, L., Che, KH., Funderburk, SF., Pan, L., Pan, N., Zhang, M., Yue, Z.*, Zhao, Y.* (2012) \"Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG\" Nature Communications, 3,662.",
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introduction : "Pan, L., and Zhang, M.* (2012) \"Structures of Usher Syndrome 1 Proteins and Their Complexes\" Physiology, 27, 25-42. (invited review, cover story)",
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introduction : "Pan, L.#, Chen, J.#, Yu, J.#, Yu, H., and Zhang, M.* (2011) \"The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the MAGUK Family Scaffold Protein Core\" J. Biol. Chem. 286, 40069-40074.",
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introduction : "Wei, Z., Yan, J., Lu, Q., Pan, L., and Zhang, M.* (2011) \"Cargo Recognition Mechanism of Myosin X Revealed by the Structure of its Tail MyTH4-FERM Tandem in Complex with the DCC P3 Domain\" PNAS. 108, 3572-3577.",
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introduction : "Feng, W., Pan, L., and Zhang, M.* (2011) \"Combination of NMR spectroscopy and X-ray crystallography offers unique advantages for elucidation of the structural basis of protein complex assembly\" Sci.China.Life.Sci. 54, 101-111. (invited review)",
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introduction : "Wu, L.#, Pan, L.#, Wei, Z., and Zhang, M.* (2011) \"Structure of MyTH4-FERM Domains in Myosin VIIa Tail Bound to Cargo\" Science. 331, 757-760. (#:co-first authors, highlighted by Faculty of 1000, F1000 Cell Biology and F1000 Genomics & Genetics) ",
aticleUrl : "source/publication/Before2022/before2013-Structure-of-MyTH4-FERM-Domains in.pdf"
},{
imgAlt : null,
imgSrc : null,
introduction : "Diao, Y., Liu, W., Wong, CC., Wang, X., Lee, K., Cheung, PY., Pan, L., Xu, T., Han, J., Yates JR 3rd., Zhang, M., and Wu, Z.* (2010) \"Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding\" PNAS. 107, 20974-20979.",
aticleUrl : "source/publication/Before2022/before2013-Oxidation-induced.pdf"
},{
imgAlt : null,
imgSrc : null,
introduction : "Conan K. Wang., Pan, L., Chen, J., and Zhang, M.* (2010) \"Extensions of PDZ domains as important structural and functional elements\" PROTEIN & CELL. 8, 737-751. (invited review)",
aticleUrl : "source/publication/Before2022/before2013-Extensions-of-PDZ.pdf"
},{
imgAlt : null,
imgSrc : null,
introduction : "Shi, Y., Yu, J., Jia, Y., Pan, L., Shen, C., Xia, J., and Zhang, M.* (2010) \"Redox-regulated lipid membrane binding of the PICK1 PDZ domain\" Biochemistry. 49, 4432-443",
aticleUrl : "source/publication/Before2022/before2013-Redox-Regulated.pdf"
},{
imgAlt : null,
imgSrc : null,
introduction : "Yan, J.#, Pan, L.#, Chen, X., Wu, L., and Zhang, M.* (2010) \"The Structure of the Harmonin/Sans Complex Reveals an Unexpected Interaction Mode of the Two Usher Syndrome Proteins\" PNAS. 107, 4040-4045. (#: co-first authors)",
aticleUrl : "source/publication/Before2022/before2013-The-structure-of-the-harmoninsans.pdf"
},{
imgAlt : null,
imgSrc : null,
introduction : "Wen, W., Yu, J., Pan, L. Wei, Z., Weng, J., Wang, W., Yan, S., Tran, T., Hong, W., and Zhang, M.* (2010) \"Lipid-induced Conformational Switch Controls Fusion Activity of Longin Domain SNARE Ykt6\" Mol. Cell,37, 383-395.",
aticleUrl : "source/publication/Before2022/before2013-Lipid-Induced.pdf"
},{
imgAlt : null,
imgSrc : null,
introduction : "Pan, L.#, Yan, J.#, Wu, L., and Zhang, M.* (2009) \"Assembling Stable Hair-Cell Tip Link Complex via Multi-dentate Interactions between Harmonin and Cadherin23\" PNAS. 106, 5575-5580.",
aticleUrl : "source/publication/Before2022/before2013-Assembling-stable.pdf"
},{
imgAlt : null,
imgSrc : null,
introduction : "Chen, J.#, Pan, L.#, Wei, Z., Zhao, Y., and Zhang, M.* (2008) \"Domain Swapped Dimerization of ZO-1 PDZ2 Generates Specific and Regulatory Connexin43 Binding Sites\" EMBO J, 27, 2113-2123. (#: co-first authors)",
aticleUrl : "source/publication/Before2022/before2013-Domain-swapped.pdf"
},{
imgAlt : "",
imgSrc : null,
introduction : "Pan, L.#, Wu, H.#, Shen, C.#, Shi, Y., Jin, W., Xia, J., and Zhang, M.* (2007) \"Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes.\" EMBO J, 26, 4576-4587.",
aticleUrl : "source/publication/Before2022/before2013-Clustering-and-synaptic-targeting.pdf"
}];